Spravato® Esketamine Therapy

Behavioral Health Services in Spokane

Esketamine (Spravato®) Treatment for Depression in Spokane

The first nasal spray medication for treatment-resistant depression

Ketamine has been used as a surgical anesthesia around the world for more than 50 years. About 20 years ago, ketamine’s ability to relieve depression, anxiety, and some pain disorders in less than 24 hours after administration was stumbled upon by researchers. Follow up studies replicating the rapid results have changed researchers’ understanding of depression, revitalizing an area of medical research that had been stagnant for almost three decades. Esketamine, or Spravato®, is derived from ketamine and makes its powerful antidepressant relief available in the form of a intra-nasal spray, similar to a common nasal decongestant. Psychiatric Solutions offers esketamine therapy in our Spokane office, and this novel therapy for treatment-resistant depression can be combined with other treatments, such as antidepressants, Transcranial Magnetic Stimulation (TMS), or other therapies.


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What is esketamine therapy?

Esketamine, or Spravato®, is the first nasal spray medication that is a treatment for depression. Combined with an antidepressant, Spravato® is FDA-approved to treat treatment-resistant depression and has been clinically shown to improve symptoms of depression in just 4 weeks.

  • SPRAVATO® targets the N-methyl-D-aspartate (NMDA) receptor and is believed to work differently than currently available oral antidepressants.
  • Produces changes in the brain, reversing neural damage due to stress and depression.

Call us today at (509) 863-9779 to schedule an appointment or to learn more about the services we offer for depression treatment.

What is treatment with Spravato® like?

In a comfortable chair at our office, the patient will administer the Spravato® treatment spray under the supervision of one of our healthcare providers. Afterwards, there is a two-hour observation window to monitor for side effects.
Spravato® is administered only a couple of times each week: Two treatments per week for the first month, then one treatment per week for the second month, and one treatment every two weeks for subsequent months.

Are there any side effects with esketamine treatment?

During or shortly after treatment, esketamine therapy patients generally report some sedation and disassociation effects. Other side effects may include nausea, dizziness, vertigo, or headache.

Is esketamine therapy safe?

Spravato® has been FDA-approved for the treatment of treatment-resistant depression since 2019 and evaluated in both short- and long-term trials for safety and efficacy. Because Spravato® is administered in our office and we require a two-hour observation window after treatment, patients can be monitored closely for any adverse side effects.
Before starting esketamine therapy, we will discuss all potential side effects and interactions, and make sure Spravato® is right for you. Contact us today to schedule a consultation.